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anti-GLR antibody :: GLR Antibody

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Catalog # MBS853441
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

GLR, Antibody

Also Known As

GLR Antibody

Product Synonym Names
Glucagon receptor [Precursor]; GL-R; GCGR
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
477
OMIM
138033
3D Structure
ModBase 3D Structure for P47871
Species Reactivity
Human, Mouse, Rat
Specificity
GLR antibody detects endogenous levels of total GLR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GLR.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-GLR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GLR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GLR antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-GLR antibody
anti-GLR antibody Testing Data image
Western Blot (WB) of anti-GLR antibody
Peptide-+ Western blot analysis of extracts from COLO205 cells, using GLR antibody. Immunofluorescence analysis of HeLa cells, using GLR antibody.
anti-GLR antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GLR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,009 Da
NCBI Official Full Name
glucagon receptor
NCBI Official Synonym Full Names
glucagon receptor
NCBI Official Symbol
NCBI Official Synonym Symbols
GGR; GL-R
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NCBI Protein Information
glucagon receptor
UniProt Protein Name
Glucagon receptor
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for GLR
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
UniProt Comments for GLR
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Product References and Citations for anti-GLR antibody
Macneil D.J., Biochem. Biophys. Res. Commun. 198:328-334(1994). Lok S., Gene 140:203-209(1994). Menzel S., Genomics 20:327-328(1994).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-GLR antibody
 Reference Product  PubMed Publications
 GCG antibody  >4 publications with GLR and GCG
Organs/Tissues associated with anti-GLR antibody
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