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GP6 elisa kit :: Bovine Glycoprotein VI, Platelet ELISA Kit

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Catalog # MBS015442
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
GP6 elisa kit
Product Name

Glycoprotein VI, Platelet (GP6), ELISA Kit

Popular Item
Full Product Name

Bovine Glycoprotein VI, Platelet ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: 19; NC_000019.9 (55525073..55549632, complement). Location: 19q13.4
OMIM
605546
3D Structure
ModBase 3D Structure for Q9HCN6
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Serum, Plasma and Tissue Homogenate
Assay Type
Sandwich
Detection Range
6.25 ng/ml - 200 ng/ml.
Sensitivity
1.0 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GP6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GP6purchase
MBS015442 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glycoprotein VI, Platelet (GP6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GP6. The ELISA analytical biochemical technique of the MBS015442 kit is based on GP6 antibody-GP6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GP6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GP6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
GP6 elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GP6 (hereafter termed this analyte) in undiluted original Bovine serum, plasma and tissue homogenate samples.
NCBI/Uniprot data below describe general gene information for GP6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,866 Da
NCBI Official Full Name
glycoprotein VI, partial
NCBI Official Synonym Full Names
glycoprotein VI (platelet)
NCBI Official Symbol
NCBI Official Synonym Symbols
GPIV; GPVI; BDPLT11
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NCBI Protein Information
platelet glycoprotein VI; glycoprotein 6; platelet collagen receptor
UniProt Protein Name
Platelet glycoprotein VI
UniProt Synonym Protein Names
Glycoprotein 6
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
GPVI_HUMAN
NCBI Summary for GP6
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
UniProt Comments for GP6
GPVI: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. Defects in GP6 are the cause of bleeding disorder platelet-type 11 (BDPLT11). BDPLT11 is a mild to moderate bleeding disorder caused by defective platelet activation and aggregation in response to collagen. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: collagen binding; protein binding; transmembrane receptor activity; receptor activity

Biological Process: platelet activation; blood coagulation; enzyme linked receptor protein signaling pathway; leukocyte migration

Disease: Bleeding Disorder, Platelet-type, 11
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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