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anti-GPR120 antibody :: GPR120 Antibody

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Catalog # MBS855267
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

GPR120, Antibody

Full Product Name

GPR120 Antibody

Product Synonym Names
G-protein coupled receptor 120; G-protein coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor 129; GPR129; PGR4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607514
3D Structure
ModBase 3D Structure for Q5NUL3
Species Reactivity
Human, Mouse, Rat
Specificity
GPR120 antibody detects endogenous levels of total GPR120 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GPR120.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-GPR120 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GPR120 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GPR120 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-GPR120 antibody
anti-GPR120 antibody Testing Data image
Western Blot (WB) of anti-GPR120 antibody
Peptide-+ Western blot analysis of extracts from LOVO cells, using GPR120 antibody. Immunofluorescence analysis of LOVO cells, using GPR120 antibody.
anti-GPR120 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GPR120. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,494 Da
NCBI Official Full Name
free fatty acid receptor 4 isoform GPR120-S
NCBI Official Synonym Full Names
free fatty acid receptor 4
NCBI Official Symbol
FFAR4  [Similar Products]
NCBI Official Synonym Symbols
GT01; PGR4; BMIQ10; GPR120; GPR129; O3FAR1
  [Similar Products]
NCBI Protein Information
free fatty acid receptor 4
UniProt Protein Name
Free fatty acid receptor 4
UniProt Synonym Protein Names
G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; Omega-3 fatty acid receptor 1
UniProt Gene Name
FFAR4  [Similar Products]
UniProt Synonym Gene Names
GPR120; GPR129; O3FAR1; PGR4  [Similar Products]
NCBI Summary for GPR120
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for GPR120
Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
Product References and Citations for anti-GPR120 antibody
Fredriksson R., FEBS Lett. 554:381-388(2003). Hirasawa A., Nat. Med. 11:90-94(2005). Deloukas P., Nature 429:375-381(2004).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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