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anti-GPR98 antibody :: Rabbit anti-Human, Mouse GPR98 Antibody

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Catalog # MBS9385125
Unit / Price
  0.1 mL  /  $445 +1 FREE 8GB USB
anti-GPR98 antibody
Product Name

GPR98, Antibody

Popular Item
Also Known As

GPR98 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
6306
OMIM
AF055084 mRNA
3D Structure
ModBase 3D Structure for Q8WXG9
Host
Rabbit
Species Reactivity
Human, Mouse
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-GPR98 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GPR98 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for GPR98. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
162,038 Da
NCBI Official Full Name
G-protein coupled receptor 98
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor V1
NCBI Official Symbol
ADGRV1  [Similar Products]
NCBI Official Synonym Symbols
FEB4; GPR98; MASS1; USH2B; USH2C; VLGR1; VLGR1b
  [Similar Products]
NCBI Protein Information
G-protein coupled receptor 98
UniProt Protein Name
G-protein coupled receptor 98
UniProt Synonym Protein Names
Monogenic audiogenic seizure susceptibility protein 1 homolog; Usher syndrome type-2C protein; Very large G-protein coupled receptor 1
UniProt Gene Name
GPR98  [Similar Products]
UniProt Synonym Gene Names
KIAA0686; KIAA1943; MASS1; VLGR1  [Similar Products]
NCBI Summary for GPR98
This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for GPR98
GPR98: Receptor that may have an important role in the development of the central nervous system. Defects in GPR98 are the cause of Usher syndrome type 2C (USH2C). USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses. Defects in GPR98 may be a cause of familial febrile convulsions type 4 (FEB4); also known as familial febrile seizures 4. Febrile convulsions are seizures associated with febrile episodes in childhood without any evidence of intracranial infection or defined pathologic or traumatic cause. It is a common condition, affecting 2-5% of children aged 3 months to 5 years. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5q14.3

Cellular Component: cell surface; cytoplasm; receptor complex

Molecular Function: calcium ion binding; protein binding

Biological Process: maintenance of organ identity; neurological system process; photoreceptor cell maintenance; sensory perception of light stimulus; sensory perception of sound

Disease: Febrile Seizures, Familial, 4; Usher Syndrome, Type Iic
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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