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GPRC5A blocking peptide

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Catalog # MBS8243787
Unit / Price
  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
GPRC5A blocking peptide
Product Name

GPRC5A, Blocking Peptide

Full Product Name

GPRC5A Blocking Peptide

Product Synonym Names
GPCR5A; RAI3; RAIG1; Retinoic acid-induced protein 3; G-protein coupled receptor family C group 5 member A; Orphan G-protein-coupling receptor PEIG-1; Retinoic acid-induced gene 1 protein; RAIG-1
Antibody/Peptide Pairs
GPRC5A peptide (MBS8243787) is used for blocking the activity of GPRC5A antibody (MBS8242697)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604138
3D Structure
ModBase 3D Structure for Q8NFJ5
Host
Synthetic
Species Reactivity
Human, Mouse
Purity/Purification
>85%
Form/Format
Lyophilized Powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of GPRC5A blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GPRC5A blocking peptide
The peptide is used to block Anti-GPRC5A Antibody reactivity.
Applications Tested/Suitable for GPRC5A blocking peptide
Blocking (BL)
Application Notes for GPRC5A blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for GPRC5A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,251 Da
NCBI Official Full Name
Retinoic acid-induced protein 3
NCBI Official Synonym Full Names
G protein-coupled receptor class C group 5 member A
NCBI Official Symbol
GPRC5A  [Similar Products]
NCBI Official Synonym Symbols
RAI3; TIG1; RAIG1; GPCR5A; PEIG-1
  [Similar Products]
NCBI Protein Information
retinoic acid-induced protein 3
UniProt Protein Name
Retinoic acid-induced protein 3
UniProt Synonym Protein Names
G-protein coupled receptor family C group 5 member A; Phorbol ester induced gene 1
UniProt Gene Name
GPRC5A  [Similar Products]
UniProt Synonym Gene Names
GPCR5A; RAI3; RAIG1; PEIG-1; RAIG-1  [Similar Products]
UniProt Entry Name
RAI3_HUMAN
NCBI Summary for GPRC5A
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]
UniProt Comments for GPRC5A
RAIG1: a G protein coupled receptor that is induced by all-trans retinoic acid (ATRA). Retinoic acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. RAIG1 is expressed in lung tissue and in several lung cancer cell lines. This retinoic acid-inducible GPCR provides evidence for an interaction between retinoid and G-protein signaling pathways.

Protein type: Receptor, GPCR; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13.1

Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of epidermal growth factor receptor activity; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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