Q8NFJ5.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,251 Da
NCBI Official Full Name
Retinoic acid-induced protein 3
NCBI Official Synonym Full Names
G protein-coupled receptor class C group 5 member A
NCBI Official Synonym Symbols
RAI3; TIG1; RAIG1; GPCR5A; PEIG-1 [Similar Products]
NCBI Protein Information
retinoic acid-induced protein 3
UniProt Protein Name
Retinoic acid-induced protein 3
UniProt Synonym Protein Names
G-protein coupled receptor family C group 5 member A; Phorbol ester induced gene 1
UniProt Synonym Gene Names
UniProt Entry Name
RAI3_HUMAN
NCBI Summary for GPRC5A
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]
UniProt Comments for GPRC5A
RAIG1: a G protein coupled receptor that is induced by all-trans retinoic acid (ATRA). Retinoic acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. RAIG1 is expressed in lung tissue and in several lung cancer cell lines. This retinoic acid-inducible GPCR provides evidence for an interaction between retinoid and G-protein signaling pathways.
Protein type: Receptor, GPCR; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12p13.1
Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane
Molecular Function: G-protein coupled receptor activity; protein binding
Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of epidermal growth factor receptor activity; signal transduction
Research Articles on GPRC5A
Precautions
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Disclaimer
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Pathways associated with GPRC5A blocking peptide
Diseases associated with GPRC5A blocking peptide
Organs/Tissues associated with GPRC5A blocking peptide
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