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GS elisa kit :: Human Glutamine Synthetase ELISA Kit

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Catalog # MBS019167
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
GS elisa kit
Product Name

Glutamine Synthetase (GS), ELISA Kit

Popular Item
Full Product Name

Human Glutamine Synthetase ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Chromosome Location
Chromosome: 1; NC_000001.10 (182350839..182361341, complement). Location: 1q31
OMIM
138290
3D Structure
ModBase 3D Structure for P15104
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Serum, Plasma and Tissue Homogenate
Assay Type
Sandwich
Detection Range
3.12 U/L - 100 U/L.
Sensitivity
1.0 U/L.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forGSpurchase
MBS019167 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glutamine Synthetase (GS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GS. The ELISA analytical biochemical technique of the MBS019167 kit is based on GS antibody-GS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
GS elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GS (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS019167. Click to request current manual
NCBI/Uniprot data below describe general gene information for GS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,064 Da
NCBI Official Full Name
glutamine synthetase
NCBI Official Synonym Full Names
glutamate-ammonia ligase
NCBI Official Symbol
NCBI Official Synonym Symbols
GS; GLNS; PIG43; PIG59
  [Similar Products]
NCBI Protein Information
glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59
UniProt Protein Name
Glutamine synthetase
UniProt Synonym Protein Names
Glutamate decarboxylase (EC:4.1.1.15); Glutamate--ammonia ligase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
GLNS; GS  [Similar Products]
UniProt Entry Name
GLNA_HUMAN
NCBI Summary for GS
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
UniProt Comments for GS
GLUL: This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner. Essential for proliferation of fetal skin fibroblasts. Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD). CSGD is a rare developmental disorder with severe brain malformation resulting in multi-organ failure and neonatal death. Glutamine is largely absent from affected patients serum, urine and cerebrospinal fluid. Belongs to the glutamine synthetase family.

Protein type: Ligase; Energy Metabolism - nitrogen; Amino Acid Metabolism - arginine and proline; EC 4.1.1.15; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 6.3.1.2

Chromosomal Location of Human Ortholog: 1q31

Cellular Component: protein complex; rough endoplasmic reticulum; mitochondrion; cytoplasm; perikaryon; nerve terminal; cytosol; nucleus

Molecular Function: glutamate-ammonia ligase activity; identical protein binding; dynein light chain binding; glutamate binding; glutamate decarboxylase activity; manganese ion binding; magnesium ion binding; ATP binding

Biological Process: glutamate catabolic process; cell proliferation; synaptic transmission; glutamine biosynthetic process; response to glucose stimulus; neurotransmitter uptake; positive regulation of insulin secretion; amino acid biosynthetic process; cellular response to starvation; positive regulation of synaptic transmission, glutamatergic; positive regulation of epithelial cell proliferation; protein homooligomerization

Disease: Glutamine Deficiency, Congenital
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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