NP_001627.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,866 Da
NCBI Official Full Name
ADP/ATP translocase 3
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
NCBI Official Synonym Symbols
2; 3; ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y [Similar Products]
NCBI Protein Information
ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP/ATP translocator of liver; ADP,ATP carrier protein, liver; adenine nucleotide translocator 3; solute carrier family 25 member 6; ADP,ATP carrier protein, isoform T2
UniProt Protein Name
ADP/ATP translocase 3
UniProt Synonym Protein Names
ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6Cleaved into the following chain:ADP/ATP translocase 3, N-terminally processed
UniProt Synonym Gene Names
UniProt Entry Name
ADT3_HUMAN
NCBI Summary for SLC25A6
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
UniProt Comments for SLC25A6
SLC25A6: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Belongs to the mitochondrial carrier family.
Protein type: Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3
Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus; mitochondrial inner membrane presequence translocase complex
Molecular Function: protein binding; ATP:ADP antiporter activity
Biological Process: ATP transport; ADP transport; cellular protein metabolic process; viral reproduction; apoptosis; active induction of host immune response by virus; virus-host interaction; energy reserve metabolic process; viral infectious cycle; transmembrane transport; regulation of insulin secretion; protein targeting to mitochondrion
Research Articles on SLC25A6
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Pathways associated with SLC25A6 elisa kit
Organs/Tissues associated with SLC25A6 elisa kit
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