NP_001287876.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,326 Da
NCBI Official Full Name
cleavage and polyadenylation specificity factor subunit 6 isoform 2
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 6, 68kDa
NCBI Official Synonym Symbols
CFIM; CFIM68; HPBRII-4; HPBRII-7 [Similar Products]
NCBI Protein Information
cleavage and polyadenylation specificity factor subunit 6; protein HPBRII-4/7; CPSF 68 kDa subunit; pre-mRNA cleavage factor Im (68kD); pre-mRNA cleavage factor I, 68kD subunit; cleavage factor Im complex 68 kDa subunit; pre-mRNA cleavage factor Im 68 kDa subunit; cleavage and polyadenylation specificity factor 68 kDa subunit
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 6
UniProt Synonym Protein Names
Cleavage and polyadenylation specificity factor 68 kDa subunit; CFIm68; CPSF 68 kDa subunit; Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII-4/7
UniProt Synonym Gene Names
UniProt Entry Name
CPSF6_HUMAN
NCBI Summary for CPSF6
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for CPSF6
CPSF6: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. Belongs to the RRM CPSF6/7 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: nucleoplasm; membrane; ribonucleoprotein complex; nucleus; paraspeckles; mRNA cleavage factor complex
Molecular Function: mRNA binding; protein binding; RNA binding; nucleotide binding
Biological Process: mRNA polyadenylation; mRNA processing; protein tetramerization
Research Articles on CPSF6
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with CPSF6 elisa kit
Pathways associated with CPSF6 elisa kit
Diseases associated with CPSF6 elisa kit
Organs/Tissues associated with CPSF6 elisa kit
|