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GUK1 recombinant protein :: Guanylate kinase Recombinant Protein

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Catalog # MBS1476775
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $745 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $895 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,135 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,630 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,720 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,725 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,180 +2 FREE 8GB USB
SDS-PAGE
Product Name

Guanylate kinase (GUK1), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Guanylate kinase

Product Synonym Names
GMP kinase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-197aa; Full Length
Sequence Length
197
Sequence
SGPRPVVLSG PSGAGKSTLL KRLLQEHSGI FGFSVSHTTR NPRPGEENGK DYYFVTREVM QRDIAAGDFI EHAEFSGNLY GTSKVAVQAV QAMNRICVLD VDLQGVRNIK ATDLRPIYIS VQPPSLHVLE QRLRQRNTET EESLVKRLAA AQADMESSKE PGLFDVVIIN DSLDQAYAEL KEALSEEIKK AQRTGA
OMIM
139270
3D Structure
ModBase 3D Structure for Q16774
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of GUK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GUK1 recombinant protein
Essential for recycling GMP and indirectly, cGMP.
Product Categories/Family for GUK1 recombinant protein

GUK1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for GUK1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37.58kD
NCBI Official Full Name
guanylate kinase isoform b
NCBI Official Synonym Full Names
guanylate kinase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
guanylate kinase
UniProt Protein Name
Guanylate kinase
UniProt Synonym Protein Names
GMP kinase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
KGUA_HUMAN
NCBI Summary for GUK1
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for GUK1
GUK1: Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, other; Nucleotide Metabolism - purine; EC 2.7.4.8

Chromosomal Location of Human Ortholog: 1q32-q41

Cellular Component: cytosol

Molecular Function: ATP binding; guanylate kinase activity

Biological Process: ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; drug metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; GMP metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleotide phosphorylation; purine nucleotide metabolic process
Product References and Citations for GUK1 recombinant protein
"Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation." Fitzgibbon J., Katsanis N., Wells D., Delhanty J., Vallins W., Hunt D.M. FEBS Lett. 385:185-188(1996)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withGUK1 recombinant protein
 Reference Product  PubMed Publications
 NME1 recombinant protein  >1 publications with GUK1 and NME1
Diseases associated with GUK1 recombinant protein
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