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HA recombinant protein :: HA (H5N8)(A/duck/NY/191255-59/02) Recombinant Protein

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Catalog # MBS434084
Unit / Price
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  0.05 mg  /  $380 +1 FREE 8GB USB
Testing Data
Product Name

HA (H5N8)(A/duck/NY/191255-59/02), Recombinant Protein

Full Product Name

HA (H5N8)(A/duck/NY/191255-59/02) (aa 1-490)

Product Synonym Names
HA (H5N8)(A/duck/NY/191255-59/02); glycosylated recombinant protein; HA (aa 1-490)(H5N8)(A/duck/NY/191255-59/02); HA (H5N8)(A/duck/NY/191255-59/02) (aa 1-490), glycosylated recombinant protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
293 cell culture
Purity/Purification
>= 95% (SDS-PAGE)
Concentration
1 mug/mul in PBS. (lot specific)
Viral Protein
C-terminal 6xHis tagged hemagglutinin protein HA (amino acid 1-490)(H5N8)(A/duck/NY/191255-59/02) (Genebank No. AAP72011).
Preparation and Storage
Store at -20 degree C. Stable for 6-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
Other Notes
Small volumes of HA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HA recombinant protein
Description: 6xHis tagged Hemagglutinin (amino acid 1-490) (H5N8)(A/duck/NY/191255-59/02) (Genebank No.AAP72011)
Viral protein purified from 293 cell culture.
Introduction: Influenza hemagglutinin (HA) is a type of hemagglutinin found on the surface of the influenza viruses. HA is an antigenic glycoprotein, like all other hemagglutinins, it causes red blood cells to agglutinate. HA is responsible for binding the virus to the cell that is being infected. HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes.
HA is a homotrimeric integral membrane glycoprotein. HA monomer is synthesized as a single polypeptide that is subsequently cleaved into two smaller polypeptides, the HA1 and HA2 subunits. Each HA monomer consists of a long, helical chain anchored in the membrane by HA2 and topped by a large HA1 globule.
Applications Tested/Suitable for HA recombinant protein
Western Blot (WB), ELISA (EIA)
Application Notes for HA recombinant protein
SDS-PAGE Data: purified HA (H5N8)(A/duck/NY/191255-59/02) protein.

Testing Data of HA recombinant protein
HA recombinant protein Testing Data image
NCBI/Uniprot data below describe general gene information for HA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
Molecular Weight
61,973 Da
NCBI Official Full Name
hemagglutinin, partial
UniProt Protein Name
Hemagglutinin
Protein Family
UniProt Gene Name
UniProt Entry Name
Q7TE93_9INFA
UniProt Comments for HA
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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