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HCV recombinant protein :: Hepatitis C Virus NS4 a+b Recombinant Protein

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Catalog # MBS142579
Unit / Price
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  0.1 mg  /  $225 +1 FREE 8GB USB
  0.5 mg  /  $645 +1 FREE 8GB USB
  1 mg  /  $1,220 +1 FREE 8GB USB
HCV recombinant protein
Product Name

Hepatitis C Virus NS4 a+b (HCV), Recombinant Protein

Popular Item
Full Product Name

Recombinant Hepatitis C Virus NS4 a+b

Product Synonym Names
HCV NS4 a+b; Hepatitis C Virus NS4 a+b Recombinant; HCV NS4 a+b
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
1658 TWVLVGGVLA ALAAYCLSTG CVVIVGRVVL SGKPAIIPDR EVLYREFDEM EECSQHLPYI EQGMMLAEQF KQKALGLLQT ASRQAEVIAP AVQTNWQKLE TFWAKHMWNF ISGIQYLAGL STLPGNPAIA SLMAFTAAVT SPLTTSQTLL FNILGGWVAA QLAAPGAATA FVGAGLAGAA IGSVGLGKVL IDILAGYGAG VAGAL 1863
Specificity
Immunoreactive with sera of HCV-infected individuals.
Purity/Purification
HCV NS4 a+b protein is >95% pure as determined by 10% PAGE (coomassie staining).
HCV NS4 a+b protein was purified by proprietary chromatographic technique.
Form/Format
20mM Tris-Hcl pH 8, 8M urea.
Concentration
1mg/ml (lot specific)
Preparation and Storage
HCV NS4 a+b although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Other Notes
Small volumes of HCV recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HCV recombinant protein
Description: The E Coli derived 19 kDa recombinant protein contains the HCV NS4 immunodominant regions, amino acids 1658-1863. The protein is fused with b-galactosidase (114 kDa) at N-terminus, pI 5.45.

Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Applications Tested/Suitable for HCV recombinant protein
ELISA (EIA), Western Blot (WB)
Application Notes for HCV recombinant protein
HCV NS4 a+b antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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