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HERPUD1 cdna clone

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Catalog # MBS1269048
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
HERPUD1 cdna clone
Product Name

HERPUD1, cDNA Clone

Popular Item
Also Known As

HERPUD1 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
699
Sequence
atggagtccg agaccgaacc cgagcccgtc acgctcctgg tgaagagccc caaccagcgc caccgcgact tggagctgag tggcgaccgc ggctggagtg tgggccacct caaggcccac ctgagccgcg tctaccccga gcgtccgcgt ccagaggacc agaggttaat ttattctggg aagctgttgt tggatcacca atgtctcagg gacttgcttc caaaggaaaa acggcatgtt ttgcatctgg tgtgcaatgt gaagagtcct tcaaaaatgc cagaaatcaa cgccaaggtg gctgaatcca cagaggagcc tgctggttct aatcggggac agtatcctga ggattcctca agtgatggtt taaggcaaag ggaagttctt cggaaccttt cttcccctgg atgggaaaac atctcaaggc atcacgttgg gtggtttcca tttagaccga ggccggttca gaacttccca aatgatggtc ctcctcctga cgttgtaaat caggacccca acaataactt acaggaaggc actgatcctg aaactgaaga ccccaaccac ctccctccag acagggatgt actagatggc gagcagacca gcccctcctt tatgagcaca gcatggcttg tcttcaagac tttctttgcc tctcttcttc cagaaggccc cccagccatc gcaaactga
OMIM
608070
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of HERPUD1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for HERPUD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,851 Da
NCBI Official Full Name
Homo sapiens homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, mRNA
NCBI Official Synonym Full Names
homocysteine inducible ER protein with ubiquitin like domain 1
NCBI Official Symbol
HERPUD1  [Similar Products]
NCBI Official Synonym Symbols
SUP; HERP; Mif1
  [Similar Products]
NCBI Protein Information
homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
UniProt Protein Name
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
UniProt Synonym Protein Names
Methyl methanesulfonate (MMF)-inducible fragment protein 1
UniProt Gene Name
HERPUD1  [Similar Products]
UniProt Synonym Gene Names
HERP; KIAA0025; MIF1  [Similar Products]
UniProt Entry Name
HERP1_HUMAN
NCBI Summary for HERPUD1
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
UniProt Comments for HERPUD1
HERPUD1: Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane

Molecular Function: protein binding

Biological Process: endoplasmic reticulum calcium ion homeostasis; response to unfolded protein; retrograde protein transport, ER to cytosol
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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