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HIST1H4A recombinant protein :: Histone H4 (HIST1H4A) Recombinant Protein

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Catalog # MBS952068
Unit / Price
  0.05 mg (E-Coli)  /  $495 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $660 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $725 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $820 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $900 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,010 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,020 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,035 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,060 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,500 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,530 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,620 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,010 +2 FREE 8GB USB
HIST1H4A recombinant protein
Product Name

Histone H4 (HIST1H4A), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Histone H4 (HIST1H4A)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-103aa, Full Length of Mature Protein
Sequence Length
103
Sequence
SGRGKGGKGL GKGGAKRHRK VLRDNIQGIT KPAIRRLARR GGVKRISGLI YEETRGVLKV FLENVIRDAV TYTEHAKRKT VTAMDVVYAL KRQGRTLYGF GG
OMIM
142750
3D Structure
ModBase 3D Structure for P62805
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of HIST1H4A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HIST1H4A recombinant protein
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
NCBI/Uniprot data below describe general gene information for HIST1H4A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,367 Da
NCBI Official Full Name
histone H4
NCBI Official Synonym Full Names
histone cluster 2 H4 family member b
NCBI Official Symbol
HIST2H4B  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
histone H4
UniProt Protein Name
Histone H4
UniProt Gene Name
HIST1H4A  [Similar Products]
UniProt Synonym Gene Names
H4/A; H4FA  [Similar Products]
NCBI Summary for HIST1H4A
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Aug 2015]
UniProt Comments for HIST1H4A
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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