P35915.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
31,436 Da
NCBI Official Full Name
Hydroxymethylglutaryl-CoA lyase, mitochondrial
NCBI Official Synonym Full Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase
NCBI Official Synonym Symbols
NCBI Protein Information
hydroxymethylglutaryl-CoA lyase, mitochondrial; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
UniProt Protein Name
Hydroxymethylglutaryl-CoA lyase, mitochondrial
UniProt Synonym Protein Names
3-hydroxy-3-methylglutarate-CoA lyase
UniProt Synonym Gene Names
UniProt Entry Name
HMGCL_CHICK
UniProt Comments for HMGCL
Function: Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism
Catalytic activity: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate.
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Pathways associated with HMGCL elisa kit
Organs/Tissues associated with HMGCL elisa kit
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