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HMGCS elisa kit :: Canine 3-Hydroxy-3-methylglutaryl-Coenzyme A Synthase ELISA Kit

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Catalog # MBS747369
Unit / Price
  48-Strip-Wells  /  $440 +1 FREE 8GB USB
  96-Strip-Wells  /  $640 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
HMGCS elisa kit
Product Name

3-Hydroxy-3-methylglutaryl-Coenzyme A Synthase (HMGCS), ELISA Kit

Also Known As

Canine 3-Hydroxy-3-methylglutaryl-Coenzyme A Synthase ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
142940
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of HMGCS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forHMGCSpurchase
MBS747369 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 3-Hydroxy-3-methylglutaryl-Coenzyme A Synthase (HMGCS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HMGCS. The ELISA analytical biochemical technique of the MBS747369 kit is based on HMGCS antibody-HMGCS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HMGCS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HMGCS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for HMGCS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,294 Da
NCBI Official Full Name
hydroxymethylglutaryl-CoA synthase, cytoplasmic
NCBI Official Synonym Full Names
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
NCBI Official Symbol
HMGCS1  [Similar Products]
NCBI Official Synonym Symbols
HMGCS
  [Similar Products]
NCBI Protein Information
hydroxymethylglutaryl-CoA synthase, cytoplasmic; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
UniProt Protein Name
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Synonym Protein Names
3-hydroxy-3-methylglutaryl coenzyme A synthase
UniProt Gene Name
HMGCS1  [Similar Products]
UniProt Synonym Gene Names
HMGCS; HMG-CoA synthase  [Similar Products]
UniProt Entry Name
HMCS1_HUMAN
UniProt Comments for HMGCS
HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.

Protein type: Lipid Metabolism - synthesis and degradation of ketone bodies; EC 2.3.3.10; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation

Chromosomal Location of Human Ortholog: 5p14-p13

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus; cytosol

Molecular Function: protein homodimerization activity; organic acid binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; drug binding

Biological Process: response to drug; response to purine; isoprenoid biosynthetic process; male gonad development; cellular lipid metabolic process; liver development; cholesterol biosynthetic process; response to low light intensity; response to vitamin E; response to tellurium ion; response to lipoprotein stimulus; lipid metabolic process; brain development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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