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HNRPLL cdna clone

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Catalog # MBS1266431
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
HNRPLL cdna clone
Product Name

HNRPLL, cDNA Clone

Popular Item
Full Product Name

HNRPLL cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgttggctc gggagacgta cgaggaggac cgggagtacg agagccaggc caagcgtctc aagaccgagg agggggagat cgactactcg gccgaggaag gcgagaaccg ccgggaagcg acgccccggg gcgggggcga tggcggcggc ggcggccgga gcttctctca gccggaggca ggtggaagtc atcataaagt ttctgtttca cccgtcgtcc atgttcgagg actctgtgaa tctgtggtgg aagcagacct cgtggaagcg ctggaaaaat ttgggacaat atgctatgtg atgatgatgc catttaaacg acaggctcta gtggaatttg aaaacataga tagtgccaaa gaatgtgtga catttgctgc agatgaaccc gtgtacattg ctggtcaaca ggcttttttc aactattcta caagcaaaag gatcactcgg ccaggaaata ctgatgatcc atcaggaggc aacaaagttc ttctgctctc aattcagaat ccgctttatc caattacagt ggatgtttta tatactgtat gcaaccctgt tggcaaagtg caacgtattg ttatattcaa gagaaatggg atacaagcaa tggttgagtt tgaatcagtc ctttgtgccc agaaagctaa agcagcactc aatggagctg atatatatgc tggatgttgc acactaaaaa ttgaatatgc acggccaact cgtctaaatg ttattaggaa tgacaatgac agttgggact acactaaacc atatttggga agacgaggta ggtattttat acattttaga atgtacttga tctgctga
OMIM
611208
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of HNRPLL cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for HNRPLL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,467 Da
NCBI Official Full Name
Homo sapiens heterogeneous nuclear ribonucleoprotein L-like, mRNA
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein L like
NCBI Official Symbol
HNRNPLL  [Similar Products]
NCBI Official Synonym Symbols
SRRF; HNRPLL
  [Similar Products]
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein L-like
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein L-like
UniProt Synonym Protein Names
Stromal RNA-regulating factor
UniProt Gene Name
HNRNPLL  [Similar Products]
UniProt Synonym Gene Names
HNRPLL; SRRF; hnRNPLL  [Similar Products]
UniProt Entry Name
HNRLL_HUMAN
NCBI Summary for HNRPLL
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
UniProt Comments for HNRPLL
HNRPLL: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 2p22.1

Cellular Component: membrane

Molecular Function: mRNA binding; protein binding

Biological Process: positive regulation of RNA splicing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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