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HP recombinant protein :: Haptoglobin (HP) Recombinant Protein

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Catalog # MBS1301439
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $795 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $885 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,065 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,115 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,175 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,355 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,355 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,610 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,775 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,095 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,150 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,200 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,240 +4 FREE 8GB USB
HP recombinant protein
Product Name

Haptoglobin (HP), Recombinant Protein

Full Product Name

Recombinant Bovine Haptoglobin (HP)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
19-401aa, Full Length of Mature Protein
Sequence
VETGSEATAD SCPKAPEIAN SHVEYSVRYQ CDKYYKLHAG NGVYTFNNKQ WINKDIGQQL PECEEDDSCP EPPKIENGYV EYLVRYQCKP YYTLRTCGDG VYTFNSKKQW INKNIGQKLP ECEAVCGKPK HPVDQVQRII GGSLDAKGSF PWQAKMVSQH NLISGATLIN ERWLLTTAKN LYLGHSSDKK AKDITPTLRL YVGKNQLVEV EKVVLHPDHS KVDIGLIKLR QKVPVNDKVM PICLPSKDYV KVGRVGYVSG WGRNENFNFT EHLKYVMLPV ADQDKCVKHY EGVDAPKNKT AKSPVGVQPI LNENTFCVGL SKYQDDTCYG DAGSAFVVHD KEDDTWYAAG ILSFDKSCAV AEYGVYVKVT SILDWVRKTI ANN
3D Structure
ModBase 3D Structure for Q2TBU0
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bovine
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HP recombinant protein
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and
or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn s disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson s disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for HP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
44,859 Da
NCBI Official Full Name
haptoglobin
NCBI Official Symbol
NCBI Protein Information
haptoglobin
UniProt Protein Name
Haptoglobin
UniProt Synonym Protein Names
Zonulin
UniProt Gene Name
UniProt Comments for HP
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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