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HRAS recombinant protein :: GTPase HRas (HRAS) Recombinant Protein

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Catalog # MBS957192
Unit / Price
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  0.05 mg (E-Coli)  /  $585 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $715 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $780 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $860 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $955 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $970 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,100 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,190 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,290 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,370 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,745 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,795 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,940 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,790 +3 FREE 8GB USB
HRAS recombinant protein
Product Name

GTPase HRas (HRAS), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human GTPase HRas (HRAS)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-186aa, Full length protein
Sequence
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ GVEDAFYTLV REIRQHKLRK LNPPDESGPG CMSCKC
OMIM
109800
3D Structure
ModBase 3D Structure for P01112
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HRAS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HRAS recombinant protein
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
NCBI/Uniprot data below describe general gene information for HRAS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,870 Da
NCBI Official Full Name
GTPase HRas isoform 1
NCBI Official Synonym Full Names
HRas proto-oncogene, GTPase
NCBI Official Symbol
NCBI Official Synonym Symbols
CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1
  [Similar Products]
NCBI Protein Information
GTPase HRas
UniProt Protein Name
GTPase HRas
UniProt Synonym Protein Names
H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HRAS1  [Similar Products]
NCBI Summary for HRAS
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for HRAS
Involved in the activation of Ras protein signal transduction (PubMed:22821884). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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