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HSD17B10 recombinant protein :: 3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) Recombinant Protein

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Catalog # MBS1183335
Unit / Price
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  0.05 mg (E-Coli)  /  $660 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $780 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $890 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $980 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,010 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,055 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,250 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,460 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,475 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,895 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,910 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,040 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,960 +3 FREE 8GB USB
HSD17B10 recombinant protein
Product Name

3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10), Recombinant Protein

Full Product Name

Recombinant Bovine 3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-261aa, Full Length of Mature Protein
Sequence
AAACRSVKGL VALITGGASG LGLATAERLV GQGATAVLLD LPNSDGETQA KKLGKSCAFA PADVTSEKDV QAALTLAREK FGRVDVAVNC AGIAVASKTY NLKKSQAHTL EDFQRVINVN LIGTFNVIRL VAGEMGQNEP DQGGQRGVII NTASVAAFEG QVGQAAYSAS KGGIVGMTLP IARDLAPMGI RVMTIAPGLF GTPLLTTLPD KVRNFLASQV PFPSRLGDPA EYAHLVQAII ENSFLNGEVI RLDGAIRMQP
3D Structure
ModBase 3D Structure for O02691
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bovine
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HSD17B10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HSD17B10 recombinant protein
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase
reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
NCBI/Uniprot data below describe general gene information for HSD17B10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,140 Da
NCBI Official Full Name
3-hydroxyacyl-CoA dehydrogenase type-2
NCBI Official Synonym Full Names
hydroxysteroid 17-beta dehydrogenase 10
NCBI Official Symbol
HSD17B10  [Similar Products]
NCBI Official Synonym Symbols
HADH2
  [Similar Products]
NCBI Protein Information
3-hydroxyacyl-CoA dehydrogenase type-2
UniProt Protein Name
3-hydroxyacyl-CoA dehydrogenase type-2
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase 10 (EC:1.1.1.51
UniProt Gene Name
HSD17B10  [Similar Products]
UniProt Synonym Gene Names
HADH2; Mitochondrial RNase P protein 2  [Similar Products]
UniProt Comments for HSD17B10
Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). Essential for structural and functional integrity of mitochondria.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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