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HSPD1 recombinant protein :: 60 kDa heat shock protein, mitochondrial (HSPD1) Recombinant Protein

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Catalog # MBS955999
Unit / Price
  0.05 mg (E-Coli)  /  $970 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,165 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,305 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,405 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,415 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,435 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,475 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,590 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $2,045 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,115 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,130 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,420 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,780 +3 FREE 8GB USB
SDS-PAGE
Product Name

60 kDa heat shock protein, mitochondrial (HSPD1), Recombinant Protein

Popular Item
Also Known As

Recombinant Human 60 kDa heat shock protein, mitochondrial (HSPD1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-573aa, Full Length of Mature Protein
Sequence Length
158
Sequence
AKDVKFGADA RALMLQGVDL LADAVAVTMG PKGRTVIIEQ SWGSPKVTKD GVTVAKSIDL KDKYKNIGAK LVQDVANNTN EEAGDGTTTA TVLARSIAKE GFEKISKGAN PVEIRRGVML AVDAVIAELK KQSKPVTTPE EIAQVATISA NGDKEIGNII SDAMKKVGRK GVITVKDGKT LNDELEIIEG MKFDRGYISP YFINTSKGQK CEFQDAYVLL SEKKISSIQS IVPALEIANA HRKPLVIIAE DVDGEALSTL VLNRLKVGLQ VVAVKAPGFG DNRKNQLKDM AIATGGAVFG EEGLTLNLED VQPHDLGKVG EVIVTKDDAM LLKGKGDKAQ IEKRIQEIIE QLDVTTSEYE KEKLNERLAK LSDGVAVLKV GGTSDVEVNE KKDRVTDALN ATRAAVEEGI VLGGGCALLR CIPALDSLTP ANEDQKIGIE IIKRTLKIPA MTIAKNAGVE GSLIVEKIMQ SSSEVGYDAM AGDFVNMVEK GIIDPTKVVR TALLDAAGVA SLLTTAEVVV TEIPKEEKDP GMGAMGGMGG GMGGGMF
OMIM
118190
3D Structure
ModBase 3D Structure for P10809
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of HSPD1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HSPD1 recombinant protein
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

HSPD1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for HSPD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,100 Da
NCBI Official Full Name
60 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock protein family D (Hsp60) member 1
NCBI Official Symbol
HSPD1  [Similar Products]
NCBI Official Synonym Symbols
HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60
  [Similar Products]
NCBI Protein Information
60 kDa heat shock protein, mitochondrial
UniProt Protein Name
60 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein
Protein Family
UniProt Gene Name
HSPD1  [Similar Products]
UniProt Synonym Gene Names
HSP60; CPN60; HSP-60; Hsp60  [Similar Products]
NCBI Summary for HSPD1
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
UniProt Comments for HSPD1
Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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