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HTR1A recombinant protein :: 5-hydroxytryptamine receptor 1A (HTR1A) Recombinant Protein

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Catalog # MBS956931
Unit / Price
Scan QR to view Datasheet
  0.5 mg (E-Coli)  /  $795 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $795 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,020 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,020 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,060 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,060 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,520 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,520 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,520 +1 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
HTR1A recombinant protein
Product Name

5-hydroxytryptamine receptor 1A (HTR1A), Recombinant Protein

Full Product Name

Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-36. Partial, provide the first complete extracellular domain at the N-terminal.
Sequence
MDVLSPGQGN NTTSPPAPFE TGGNTTGISD VTVSYQ
OMIM
109760
3D Structure
ModBase 3D Structure for P08908
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HTR1A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for HTR1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,107 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 1A
NCBI Official Symbol
HTR1A  [Similar Products]
NCBI Official Synonym Symbols
G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
G-21; Serotonin receptor 1A
UniProt Gene Name
HTR1A  [Similar Products]
UniProt Synonym Gene Names
ADRB2RL1; ADRBRL1; 5-HT-1A; 5-HT1A  [Similar Products]
NCBI Summary for HTR1A
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
UniProt Comments for HTR1A
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with HTR1A recombinant protein
Organs/Tissues associated with HTR1A recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >51 publications with HTR1A and Brain
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