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Htr1a recombinant protein :: 5-hydroxytryptamine receptor 1A (Htr1a) Recombinant Protein

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Catalog # MBS962045
Unit / Price Please Inquire
Htr1a recombinant protein
Product Name

5-hydroxytryptamine receptor 1A (Htr1a), Recombinant Protein

Also Known As

Recombinant Rat 5-hydroxytryptamine receptor 1A (Htr1a)

Product Synonym Names
Recombinant 5-hydroxytryptamine receptor 1A (Htr1a); 5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; Serotonin receptor 1A
Product Synonym Gene Name
Htr1a; 5ht1a[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-422
Sequence Length
422
Sequence
MDVFSFGQGN NTTASQEPFG TGGNVTSISD VTFSYQVITS LLLGTLIFCA VLGNACVVAA IALERSLQNV ANYLIGSLAV TDLMVSVLVL PMAALYQVLN KWTLGQVTCD LFIALDVLCC TSSILHLCAI ALDRYWAITD PIDYVNKRTP RRAAALISLT WLIGFLISIP PMLGWRTPED RSDPDACTIS KDHGYTIYST FGAFYIPLLL MLVLYGRIFR AARFRIRKTV RKVEKKGAGT SLGTSSAPPP KKSLNGQPGS GDWRRCAENR AVGTPCTNGA VRQGDDEATL EVIEVHRVGN SKEHLPLPSE SGSNSYAPAC LERKNERNAE AKRKMALARE RKTVKTLGII MGTFILCWLP FFIVALVLPF CESSCHMPAL LGAIINWLGY SNSLLNPVIY AYFNKDFQNA FKKIIKCKFC RR
Chromosome Location
Chromosome: 2; NC_005101.3 (55362662..55363930). Location: 2q16
3D Structure
ModBase 3D Structure for P19327
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Htr1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Htr1a. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
46,429 Da[Similar Products]
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
NCBI Official Symbol
Htr1a  [Similar Products]
NCBI Official Synonym Symbols
5HT1A; RAT5HT1A
  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1A; 5-HT1A; 5-HT-1A; serotonin receptor 1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
Serotonin receptor 1A
UniProt Gene Name
Htr1a  [Similar Products]
UniProt Synonym Gene Names
5ht1a; 5-HT-1A; 5-HT1A  [Similar Products]
UniProt Entry Name
5HT1A_RAT
NCBI Summary for Htr1a
regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD, Feb 2006]
UniProt Comments for Htr1a
5-HT(1A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. 5- hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: axon hillock; membrane; cell soma; integral to plasma membrane

Molecular Function: serotonin binding; protein binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding

Biological Process: vasoconstriction; cell proliferation; G-protein coupled receptor protein signaling pathway; positive regulation of microtubule depolymerization; behavioral fear response; serotonin receptor, adenylate cyclase inhibiting pathway; regulation of dopamine metabolic process; regulation of serotonin secretion; regulation of hormone secretion; serotonin receptor signaling pathway; serotonin metabolic process; regulation of behavior
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with Htr1a recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >2 publications with Htr1a and Mixed
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