NP_058946.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
5-hydroxytryptamine receptor 2B
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
NCBI Protein Information
5-hydroxytryptamine receptor 2B; 5-HT2B; 5-HT-2B; 5-HT-2F; serotonin receptor 2B; stomach fundus serotonin receptor
UniProt Protein Name
5-hydroxytryptamine receptor 2B
UniProt Synonym Protein Names
5-HT-2F; Serotonin receptor 2B; Stomach fundus serotonin receptor
UniProt Synonym Gene Names
UniProt Entry Name
5HT2B_RAT
NCBI Summary for Htr2b
G-protein coupled receptor for serotonin [RGD, Feb 2006]
UniProt Comments for Htr2b
5-HT(2B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Cellular Component: neuron projection; membrane; cell soma; integral to plasma membrane; dendrite; cytoplasm; plasma membrane; synapse; intracellular; cell junction
Molecular Function: protein binding; serotonin binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding
Biological Process: heart morphogenesis; cGMP biosynthetic process; negative regulation of autophagy; phosphoinositide 3-kinase cascade; inositol phosphate metabolic process; intestine smooth muscle contraction; heart development; positive regulation of MAP kinase activity; positive regulation of cell proliferation; protein kinase C activation; neural crest cell differentiation; embryonic morphogenesis; neural crest cell migration; serotonin receptor signaling pathway; regulation of behavior; positive regulation of cytokine production; response to drug; vasoconstriction; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of nitric-oxide synthase activity; calcium-mediated signaling; positive regulation of phosphatidylinositol biosynthetic process; cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; G-protein coupled receptor internalization; phospholipase C activation; release of sequestered calcium ion into cytosol; positive regulation of cell division; positive regulation of endothelial cell proliferation; phosphorylation; positive regulation of cytokine secretion; negative regulation of apoptosis
Research Articles on Htr2b
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with Htr2b recombinant protein
Diseases associated with Htr2b recombinant protein
|