NP_001992.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
29,596 Da
NCBI Official Full Name
high affinity immunoglobulin epsilon receptor subunit alpha
NCBI Official Synonym Full Names
Fc fragment of IgE receptor Ia
NCBI Official Synonym Symbols
NCBI Protein Information
high affinity immunoglobulin epsilon receptor subunit alpha
UniProt Protein Name
High affinity immunoglobulin epsilon receptor subunit alpha
UniProt Synonym Protein Names
Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
UniProt Synonym Gene Names
UniProt Entry Name
FCERA_HUMAN
NCBI Summary for FCER1A
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
UniProt Comments for FCER1A
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Research Articles on FCER1A
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Products associated with FCER1A blocking peptide
Pathways associated with FCER1A blocking peptide
Diseases associated with FCER1A blocking peptide
Organs/Tissues associated with FCER1A blocking peptide
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