NP_001723.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,960 Da
NCBI Official Full Name
butyrophilin subfamily 1 member A1
NCBI Official Synonym Full Names
butyrophilin, subfamily 1, member A1
NCBI Protein Information
butyrophilin subfamily 1 member A1
UniProt Protein Name
Butyrophilin subfamily 1 member A1
UniProt Synonym Gene Names
UniProt Entry Name
BT1A1_HUMAN
NCBI Summary for BTN1A1
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008]
UniProt Comments for BTN1A1
BTN1A1: May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. Belongs to the immunoglobulin superfamily. BTN/MOG family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: extracellular space; integral to plasma membrane
Molecular Function: receptor activity
Research Articles on BTN1A1
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Products associated with BTN1A1 elisa kit
Diseases associated with BTN1A1 elisa kit
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