AAB97725.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,455 Da
NCBI Official Full Name
calumenin
NCBI Official Synonym Full Names
calumenin
NCBI Protein Information
calumenin
UniProt Protein Name
Calumenin
UniProt Synonym Protein Names
Crocalbin; IEF SSP 9302
UniProt Entry Name
CALU_HUMAN
NCBI Summary for CALU
The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
UniProt Comments for CALU
CALU: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. Belongs to the CREC family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; Calcium-binding
Chromosomal Location of Human Ortholog: 7q32.1
Cellular Component: Golgi apparatus; sarcoplasmic reticulum lumen; membrane; endoplasmic reticulum; melanosome; extracellular region
Molecular Function: protein binding; calcium ion binding
Biological Process: platelet activation; platelet degranulation; blood coagulation
Research Articles on CALU
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Products associated with CALU elisa kit
Pathways associated with CALU elisa kit
Diseases associated with CALU elisa kit
Organs/Tissues associated with CALU elisa kit
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