NP_005082.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,731 Da
NCBI Official Full Name
peptidoglycan recognition protein 1
NCBI Official Synonym Full Names
peptidoglycan recognition protein 1
NCBI Official Synonym Symbols
PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L [Similar Products]
NCBI Protein Information
peptidoglycan recognition protein 1
UniProt Protein Name
Peptidoglycan recognition protein 1
UniProt Synonym Protein Names
Peptidoglycan recognition protein short; PGRP-S
UniProt Synonym Gene Names
UniProt Entry Name
PGRP1_HUMAN
UniProt Comments for PGLYRP1
PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Protein type: Apoptosis; Secreted, signal peptide; Receptor, misc.; Secreted
Chromosomal Location of Human Ortholog: 19q13.2-q13.3
Cellular Component: extracellular region
Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity
Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process
Research Articles on PGLYRP1
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Organs/Tissues associated with PGLYRP1 elisa kit
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