NP_002279.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,722 Da
NCBI Official Full Name
leukocyte-associated immunoglobulin-like receptor 2 isoform a
NCBI Official Synonym Full Names
leukocyte associated immunoglobulin like receptor 2
NCBI Official Synonym Symbols
NCBI Protein Information
leukocyte-associated immunoglobulin-like receptor 2
UniProt Protein Name
Leukocyte-associated immunoglobulin-like receptor 2
UniProt Synonym Protein Names
CD_antigen: CD306
UniProt Synonym Gene Names
UniProt Entry Name
LAIR2_HUMAN
NCBI Summary for LAIR2
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
UniProt Comments for LAIR2
LAIR-2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: regulation of immune response
Research Articles on LAIR2
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Pathways associated with LAIR2 recombinant protein
Diseases associated with LAIR2 recombinant protein
Organs/Tissues associated with LAIR2 recombinant protein
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