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I 309 recombinant protein :: I-309 Recombinant Protein

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Catalog # MBS144966
Unit / Price
  0.002 mg  /  $140 +1 FREE 8GB USB
  0.01 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $5,015 +6 FREE 8GB USB
I 309 recombinant protein
Product Name

I-309 (I 309), Recombinant Protein

Also Known As

Recombinant Human I-309 (CCL1) His Tag

Product Synonym Names
I 309 Human, His; I-309 (CCL1) Human Recombinant, His Tag; Small inducible cytokine A1; CCL1; T lymphocyte-secreted protein I-309; chemokine (C-C motif) ligand 1; P500; SISe; TCA3; I-309; SCYA1; I 309 His
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
96
Sequence
MGSSHHH HHH SSGLVPRGSH MKSMQV PFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK
OMIM
182281
3D Structure
ModBase 3D Structure for P22362
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
The I-309 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 2mM DTT, 10% glycerol and 50mM NaCl.
Sterile Filtered colorless solution.
Other Notes
Small volumes of I 309 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
I 309 recombinant protein
Description: I-309 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids (24-96 a.a.) and having a molecular mass of 10.8kDa. The I-309 is purified by proprietary chromatographic techniques.

Introduction: Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. This chemokine resides in a large cluster of CC chemokines on human chromosome 17.
Product Categories/Family for I 309 recombinant protein
NCBI/Uniprot data below describe general gene information for I 309. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,992 Da
NCBI Official Full Name
C-C motif chemokine 1
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 1
NCBI Official Symbol
NCBI Official Synonym Symbols
P500; SISe; TCA3; I-309; SCYA1
  [Similar Products]
NCBI Protein Information
C-C motif chemokine 1; T lymphocyte-secreted protein I-309; inflammatory cytokine I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
UniProt Protein Name
C-C motif chemokine 1
UniProt Synonym Protein Names
Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
UniProt Gene Name
UniProt Synonym Gene Names
SCYA1  [Similar Products]
UniProt Entry Name
CCL1_HUMAN
NCBI Summary for I 309
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
UniProt Comments for I 309
CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Chemokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; chemotaxis; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with I 309 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >26 publications with I 309 and Lung
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