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Iap2 recombinant protein :: Apoptosis 2 inhibitor (Iap2) Recombinant Protein

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Catalog # MBS1438880
Unit / Price
  0.05 mg (E-Coli)  /  $920 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,230 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,360 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,375 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,430 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,525 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,930 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,045 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,075 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,320 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,690 +3 FREE 8GB USB
Iap2 recombinant protein
Product Name

Apoptosis 2 inhibitor (Iap2), Recombinant Protein

Also Known As

Recombinant Drosophila melanogaster Apoptosis 2 inhibitor (Iap2)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-498aa, full length protein
Sequence Length
498
Sequence
MTELGMELES VRLATFGEWP LNAPVSAEDL VANGFFATGN WLEAECHFCH VRIDRWEYGD QVAERHRRSS PICSMVLAPN HCGNVPRSQE SDNEGNSVVD SPESCSCPDL LLEANRLVTF KDWPNPNITP QALAKAGFYY LNRLDHVKCV WCNGVIAKWE KNDNAFEEHK RFFPQCPRVQ MGPLIEFATG KNLDELGIQP TTLPLRPKYA CVDARLRTFT DWPISNIQPA SALAQAGLYY QKIGDQVRCF HCNIGLRSWQ KEDEPWFEHA KWSPKCQFVL LAKGPAYVSE VLATTAANAS SQPATAPAPT LQADVLMDEA PAKEALALGI DGGVVRNAIQ RKLLSSGCAF STLDELLHDI FDDAGAGAAL EVREPPEPSA PFIEPCQATT SKAASVPIPV ADSIPAKPQA AEAVANISKI TDEIQKMSVA TPNGNLSLEE ENRQLKDARL CKVCLDEEVG VVFLPCGHLA TCNQCAPSVA NCPMCRADIK GFVRTFLS
3D Structure
ModBase 3D Structure for Q24307
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Iap2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Iap2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,538 Da
NCBI Official Full Name
Death-associated inhibitor of apoptosis 2, isoform A
NCBI Official Synonym Full Names
Death-associated inhibitor of apoptosis 2
NCBI Official Symbol
Diap2  [Similar Products]
NCBI Official Synonym Symbols
CG8293; D-iap2; D-IAP2; dIAP; Diap; DIAP; Diap-2; DIAP-2; diap2; dIAP2; DIAP2; DIAPII; Diha; DIHA; dILP; DmelCG8293; IAP; Iap2; IAP2; Ilp
  [Similar Products]
NCBI Protein Information
CG8293 gene product from transcript CG8293-RB
UniProt Protein Name
Death-associated inhibitor of apoptosis 2
UniProt Synonym Protein Names
Apoptosis 2 inhibitor; IAP homolog A; IAP-like protein; ILP; dILP; Inhibitor of apoptosis 2
UniProt Gene Name
Diap2  [Similar Products]
UniProt Synonym Gene Names
DIHA; Iap2; Ilp; ILP; dILP  [Similar Products]
UniProt Comments for Iap2
Required for activation of NF-kappaB transcription factors in the immune deficiency (Imd) signaling cascade which is essential for innate immune responses upon infection by Gram-negative bacteria (PubMed:16894030, PubMed:17068333). Promotes cytoplasmic cleavage of Rel and its translocation to the nucleus where it drives expression of antimicrobial peptides (PubMed:17068333, PubMed:24374974). Binds, polyubiquitinates and activates Dredd which is required for Rel-mediated induction of antimicrobial peptides (PubMed:22549468). Anti-apoptotic protein which binds, ubiquitinates and inactivates the effector caspase Drice (PubMed:18166655). Suppresses rpr and hid-dependent cell death in the eye (PubMed:8548811). However, has also been shown to have little, if any, role in the regulation of the canonical caspase-dependent apoptosis pathway (PubMed:17068333). Plays a role in regulating the expression of ion channels (PubMed:24374974).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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