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IAPP recombinant protein :: Amylin Recombinant Protein

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Catalog # MBS5304623
Unit / Price
  0.05 mg  /  $290 +1 FREE 8GB USB
SDS-PAGE
Product Name

Amylin (IAPP), Recombinant Protein

Popular Item
Also Known As

Amylin protein

Product Synonym Names
Amylin protein; Diabetes associated peptide protein; DAP protein; Insulinoma amyloid peptide protein; Islet amyloid polypeptide protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
62
OMIM
147940
Host
Human
Purity/Purification
> 90% pure
Form/Format
Supplied in liquid form in PBS buffer with 20 mM GSH
Protein Type
Recombinant
Biological Significance
Amylin selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Expression System
E Coli
Preparation and Storage
Store at 4 degree C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 degree C, avoid repeat freeze/thaw cycles
Other Notes
Small volumes of IAPP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IAPP recombinant protein
Purified recombinant Amylin protein
Product Categories/Family for IAPP recombinant protein
Applications Tested/Suitable for IAPP recombinant protein
ELISA (EIA), SDS-PAGE, Western Blot (WB)

NCBI/Uniprot data below describe general gene information for IAPP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
amylin, partial
NCBI Official Synonym Full Names
islet amyloid polypeptide
NCBI Official Symbol
NCBI Official Synonym Symbols
DAP; IAP
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NCBI Protein Information
islet amyloid polypeptide
UniProt Protein Name
Islet amyloid polypeptide
UniProt Synonym Protein Names
Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
IAPP_HUMAN
NCBI Summary for IAPP
The protein encoded by this gene is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity. [provided by RefSeq, Sep 2014]
UniProt Comments for IAPP
IAPP: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. Belongs to the calcitonin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: extracellular space; cell soma; extracellular region

Molecular Function: identical protein binding; hormone activity; receptor binding

Biological Process: negative regulation of cell differentiation; cell-cell signaling; apoptosis; eating behavior; sensory perception of pain; signal transduction; negative regulation of bone resorption; endocrine pancreas development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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