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ICA1 recombinant protein :: Islet Cell Autoantigen 1 (ICA1) Recombinant Protein

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Catalog # MBS2012459 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $155 +1 FREE 8GB USB
  0.05 mg  /  $305 +1 FREE 8GB USB
  0.1 mg  /  $470 +1 FREE 8GB USB
  0.2 mg  /  $580 +1 FREE 8GB USB
  0.5 mg  /  $1,125 +1 FREE 8GB USB
  1 mg  /  $1,680 +2 FREE 8GB USB
SDS-Page
Product Name

Islet Cell Autoantigen 1 (ICA1), Recombinant Protein

Popular Item
Also Known As

Recombinant Islet Cell Autoantigen 1 (ICA1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
457
Sequence
The target protein is fused with two N-terminal Tags, His-tag and S-tag, its sequence is listed below.
MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF-MSGHKCY SWE LQDRFAQDKS VVNKMQQKYW ETKQAFIKAT GKKEDEHVVA SDADLDAKLE LFHSIQRTCL DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC FSSQQRLALR NPLCRFHQEV ETFRHRAISD TWLTVNRMEQ YRTEYRGALL WMKDVSQELD PDLYKQMEKF RKVQTQVRLA KKNFDKLKMD VCQKVDLLGA SRCNLLSHML ATYQTTLLHF WEKTSHTMAA IHESFKG
Chromosome Location
Chromosome: 6; NC_000072.6 (8630527..8778542, complement). Location: 6 A1-A2; 6 4.38 cM
3D Structure
ModBase 3D Structure for P97411
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Organism
Mus musculus (Mouse)
Expression System
Prokaryotic expression
Residues
Met1~Gly257 (Accession # P97411) with two N-terminal Tags, His-tag and S-tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Predicted isoelectric point
8.8
Predicted Molecular Mass
35.9kDa as determined by SDS-PAGE reducing conditions.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of ICA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ICA1 recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for ICA1 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
(May be suitable for use in other assays to be determined by the end user.)

NCBI/Uniprot data below describe general gene information for ICA1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26&32&37kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
islet cell autoantigen 1 isoform 2
NCBI Official Synonym Full Names
islet cell autoantigen 1
NCBI Official Symbol
NCBI Official Synonym Symbols
69kDa; ICA69
  [Similar Products]
NCBI Protein Information
islet cell autoantigen 1; p69; ICAp69; islet cell autoantigen p69; 69 kDa islet cell autoantigen; islet cell autoantigen 1, 69 kDa
UniProt Protein Name
Islet cell autoantigen 1
UniProt Synonym Protein Names
69 kDa islet cell autoantigen; ICA69; Islet cell autoantigen p69
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Icap69; ICA69; ICAp69; p69  [Similar Products]
UniProt Entry Name
ICA69_MOUSE
UniProt Comments for ICA1
ICA1: May play a role in neurotransmitter secretion.

Protein type: Unknown function

Cellular Component: Golgi membrane; Golgi apparatus; Golgi stack; synaptic vesicle membrane; membrane; perinuclear region of cytoplasm; secretory granule membrane; dendrite; cytoplasm; synapse; cytoplasmic vesicle; cell junction; cytosol

Molecular Function: protein domain specific binding

Biological Process: transport; neurotransmitter transport; regulation of protein homodimerization activity; regulation of neurotransmitter secretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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