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anti-ICAM-1 antibody :: ICAM-1 Antibody

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Catalog # MBS856881
Unit / Price
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  0.1 mg  /  $215 +1 FREE 8GB USB
  0.05 mg  /  $225 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ICAM-1, Antibody

Popular Item
Full Product Name

ICAM-1(Phospho-Tyr512) Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
147840
3D Structure
ModBase 3D Structure for P05362
Species Reactivity
Human, Mouse, Rat
Specificity
ICAM-1 (Phospho-Tyr512) antibody detects endogenous levels of ICAM-1 only when phosphorylated at tyrosine 512.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human ICMA-1 around the phosphorylation site of tyrosine 512 (K-K-YP-R-L).
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-ICAM-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ICAM-1 antibody
Western Blot (WB)
Application Notes for anti-ICAM-1 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-ICAM-1 antibody
Western blot analysis of extracts from HUVEC cells, using ICAM-1 (Ab-512) Antibody and ICAM-1 (Phospho-Tyr512) Antibody.
anti-ICAM-1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ICAM-1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,825 Da
NCBI Official Full Name
intercellular adhesion molecule 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 1
NCBI Official Symbol
ICAM1  [Similar Products]
NCBI Official Synonym Symbols
BB2; CD54; P3.58
  [Similar Products]
NCBI Protein Information
intercellular adhesion molecule 1
UniProt Protein Name
Intercellular adhesion molecule 1
UniProt Synonym Protein Names
Major group rhinovirus receptor; CD_antigen: CD54
UniProt Gene Name
ICAM1  [Similar Products]
UniProt Synonym Gene Names
ICAM-1  [Similar Products]
NCBI Summary for ICAM-1
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
UniProt Comments for ICAM-1
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Product References and Citations for anti-ICAM-1 antibody
Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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