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IFITM1 blocking peptide

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Catalog # MBS153141
Unit / Price
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  0.05 mg  /  $140 +1 FREE 8GB USB
IFITM1 blocking peptide
Product Name

IFITM1, Blocking Peptide

Popular Item
Full Product Name

IFITM1 Peptide

Product Synonym Names
9-27; CD225; IFI17; LEU13; DSPA2a; Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; interferon induced transmembrane protein 1 (9-27)
Antibody/Peptide Pairs
IFITM1 peptide (MBS153141) is used for blocking the activity of IFITM1 antibody (MBS150415)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604456
3D Structure
ModBase 3D Structure for P13164
Form/Format
Liquid
Concentration
200 ug/mL (lot specific)
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
14 amino acids near the carboxy terminus of human IFITM1.
Preparation and Storage
Store IFITM1 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of IFITM1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for IFITM1 blocking peptide
Blocking (BL)
Application Notes for IFITM1 blocking peptide
IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
NCBI/Uniprot data below describe general gene information for IFITM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,964 Da
NCBI Official Full Name
interferon-induced transmembrane protein 1
NCBI Official Synonym Full Names
interferon induced transmembrane protein 1
NCBI Official Symbol
IFITM1  [Similar Products]
NCBI Official Synonym Symbols
9-27; CD225; IFI17; LEU13; DSPA2a
  [Similar Products]
NCBI Protein Information
interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27
UniProt Protein Name
Interferon-induced transmembrane protein 1
UniProt Synonym Protein Names
Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD_antigen: CD225
UniProt Gene Name
IFITM1  [Similar Products]
UniProt Synonym Gene Names
CD225; IFI17; DSPA2a  [Similar Products]
UniProt Entry Name
IFM1_HUMAN
UniProt Comments for IFITM1
IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: protein binding; receptor signaling protein activity

Biological Process: negative regulation of cell proliferation; positive regulation of osteoblast differentiation; ossification; regulation of immune response; cell surface receptor linked signal transduction; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus; cytokine and chemokine mediated signaling pathway; defense response to virus; negative regulation of cell migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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