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IFNA21 recombinant protein :: Interferon alpha-21 Recombinant Protein

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Catalog # MBS967866
Unit / Price
  0.01 mg (E-Coli)  /  $160 +1 FREE 8GB USB
  0.01 mg (Yeast)  /  $175 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $200 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $225 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $295 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $355 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $480 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $565 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $790 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $925 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,215 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,410 +1 FREE 8GB USB
SDS-PAGE
Product Name

Interferon alpha-21 (IFNA21), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Interferon alpha-21

Product Synonym Names
Interferon alpha-F; LeIF F
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-189aa; Full Length
Sequence
CDLPQTHSLG NRRALILLAQ MGRISPFSCL KDRHDFGFPQ EEFDGNQFQK AQAISVLHEM IQQTFNLFST KDSSATWEQS LLEKFSTELN QQLNDLEACV IQEVGVEETP LMNVDSILAV KKYFQRITLY LTEKKYSPCA WEVVRAEIMR SFSLSKIFQE RLRRKE
OMIM
147584
3D Structure
ModBase 3D Structure for P01568
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of IFNA21 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IFNA21 recombinant protein
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Product Categories/Family for IFNA21 recombinant protein

IFNA21 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for IFNA21. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23.4kD
NCBI Official Full Name
interferon alpha-21
NCBI Official Synonym Full Names
interferon, alpha 21
NCBI Official Symbol
IFNA21  [Similar Products]
NCBI Official Synonym Symbols
LeIF F; leIF-F; IFN-alphaI
  [Similar Products]
NCBI Protein Information
interferon alpha-21
UniProt Protein Name
Interferon alpha-21
UniProt Synonym Protein Names
Interferon alpha-F; LeIF F
Protein Family
UniProt Gene Name
IFNA21  [Similar Products]
UniProt Synonym Gene Names
IFN-alpha-21; LeIF F  [Similar Products]
UniProt Entry Name
IFN21_HUMAN
NCBI Summary for IFNA21
This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]
UniProt Comments for IFNA21
IFNA21: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding

Biological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response
Product References and Citations for IFNA21 recombinant protein
The structure of eight distinct cloned human leukocyte interferon cDNAs.Goeddel D.V., Leung D.W., Dull T.J., Gross M., Lawn R.M., McCandliss R., Seeburg P.H., Ullrich A., Yelverton E., Gray P.W.Nature 290:20-26(1981) A new type of leukocytic interferon.Gren E.Y., Berzin V.M., Tsimanis A.Y., Apsalon U.R., Vishnevskii Y.I., Yansone I.V., Dishler A.V., Pudova N.V., Smorodintsev A.A., Iovlev V.I., Stepanov A.N., Feldmane G.Y., Meldrais Y.A., Lozha V.P., Kavsan V.M., Efimov V.A., Sverdlov E.D.Dokl. Biochem. 269:91-95(1983) Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes.Gren E., Berzin V.M., Jansone I., Tsimanis A., Vishnevsky Y., Apsalons U.J. Interferon Res. 4:609-617(1984) DNA sequence and analysis of human chromosome 9.Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.Nature 429:369-374(2004)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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