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IFNb recombinant protein :: Interferon Beta (IFNb) Recombinant Protein

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Catalog # MBS2086770 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $145 +1 FREE 8GB USB
  0.05 mg  /  $280 +1 FREE 8GB USB
  0.1 mg  /  $440 +1 FREE 8GB USB
  0.2 mg  /  $540 +1 FREE 8GB USB
  0.5 mg  /  $1,040 +1 FREE 8GB USB
  1 mg  /  $1,545 +1 FREE 8GB USB
Product Name

Interferon Beta (IFNb), Recombinant Protein

Popular Item
Full Product Name

Recombinant Interferon Beta (IFNb)

Product Synonym Names
IFNB1; IFN-B; IFB; IFF; IFNB; Interferon Beta 1 Fibroblast
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
V00534 Genomic DNA
3D Structure
ModBase 3D Structure for P01574
Host
E Coli
Purity/Purification
> 95%
Form/Format
Freeze-dried powder
Fragment
Val22~Gln185 linked by TDSSTTTTTTTTN
Tag
N-terminal His and GST Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Source Note
Prokaryotic expression
Organism Species
Equine
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Isoelectric Point
5.7
Subcellular Location
Secreted
Usage
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of IFNb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for IFNb recombinant protein
Applications Tested/Suitable for IFNb recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)

Sequence Information of IFNb recombinant protein
IFNb recombinant protein Sequence Information image
Testing Data of IFNb recombinant protein
IFNb recombinant protein Testing Data image
NCBI/Uniprot data below describe general gene information for IFNb. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51.9kDa
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon beta 1
NCBI Official Symbol
IFNB1  [Similar Products]
NCBI Official Synonym Symbols
IFB; IFF; IFNB; IFN-beta
  [Similar Products]
NCBI Protein Information
interferon beta
UniProt Protein Name
Interferon beta
UniProt Synonym Protein Names
Fibroblast interferon
Protein Family
UniProt Gene Name
IFNB1  [Similar Products]
UniProt Synonym Gene Names
IFB; IFNB; IFN-beta  [Similar Products]
NCBI Summary for IFNb
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
UniProt Comments for IFNb
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21.3

Cellular Component: extracellular region; extracellular space

Molecular Function: chloramphenicol O-acetyltransferase activity; cytokine activity; interferon-alpha/beta receptor binding

Biological Process: B cell activation during immune response; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; defense response to virus; humoral immune response; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of viral genome replication; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription from RNA polymerase II promoter; response to exogenous dsRNA; T cell activation during immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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