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IFNB1 recombinant protein :: IFN BETA 1B Recombinant Protein

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Catalog # MBS232060
Unit / Price
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  0.01 mg  /  $525 +1 FREE 8GB USB
IFNB1 recombinant protein
Product Name

IFN BETA 1B (IFNB1), Recombinant Protein

Full Product Name

RECOMBINANT HUMAN INTERFERON BETA 1B

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
147640
3D Structure
ModBase 3D Structure for P01574
Purity/Purification
>98% by SDS PAGE and HPLC analysis.
Form/Format
Purified Recombinant protein - lyophilised.
Concentration
Approximate Protein Concentration: 0.1 mg/ml after reconstitution (lot specific)
Reconstitution
Reconstitute with 0.1ml distilled water.Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution.
Preparation
Buffer Solution
Lyophilised from a solution containing human albumin and dextrose.
Activity
The Specific activity determined using a viral resistance assay is of 32 x 106 IU/mg. The viral resistance assays used are the human WISH cell line and VSV, or the monkey VERO cell line and EMCV.
Target Species
Human
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 3 months from date of reconstitution.
Other Notes
Small volumes of IFNB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IFNB1 recombinant protein
Recombinant human interferon beta 1b produced in E Coli is a single non-glycosylated variant form of the human interferon beta-1b polypeptide chain. The interferon gene was cloned from human fibroblasts and altered to substitute Serine for the Cysteine at residue 17.
Applications Tested/Suitable for IFNB1 recombinant protein
Functional Assays (FN)
NCBI/Uniprot data below describe general gene information for IFNB1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18.5 kDa (165 amino acid residues)[Similar Products]
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon, beta 1, fibroblast
NCBI Official Symbol
IFNB1  [Similar Products]
NCBI Official Synonym Symbols
IFB; IFF; IFNB
  [Similar Products]
NCBI Protein Information
interferon beta; IFN-beta; fibroblast interferon
UniProt Protein Name
Interferon beta
UniProt Synonym Protein Names
Fibroblast interferon
Protein Family
UniProt Gene Name
IFNB1  [Similar Products]
UniProt Synonym Gene Names
IFB; IFNB; IFN-beta  [Similar Products]
UniProt Entry Name
IFNB_HUMAN
UniProt Comments for IFNB1
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; response to virus; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; cell surface receptor linked signal transduction; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein; B cell activation during immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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