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IFNG recombinant protein :: Interferon gamma Recombinant Protein

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Catalog # MBS203080
Unit / Price
  0.1 mg  /  $255 +1 FREE 8GB USB
  0.5 mg  /  $535 +1 FREE 8GB USB
SDS-Page
Product Name

Interferon gamma (IFNG), Recombinant Protein

Popular Item
Also Known As

Interferon gamma, 24-166 aa, Human, E Coli (Bioactivity Validated)

Product Synonym Names
Ifng; Interferon-g; IFN-gamma; Interferon gamma; IFNG; IFG; IFI; IFN gamma; IFN immune; Immune interferon; Interferon gamma precursor; Macrophage activating factor; MAF; T Cell interferon; Type II Interferon
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
166
Sequence
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ
OMIM
X13274 mRNA
3D Structure
ModBase 3D Structure for P01579
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4), 10% glycerol.
Concentration
1 mg/ml (determined by Absorbance at 280nm) (lot specific)
Antigen Species
Human
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Biological Activity
Measured in a cytotoxicity assay using WiDr cells. The ED50 for this effect is less or equal to 5 ng/ml.
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of IFNG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IFNG recombinant protein
Nature human interferon-gamma is composed of 143amino acid residues without cysteine residues and is glycosylated. Recombinant human interferon-gamma was expressed in E Coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Additional amino acid (Methionine) is attached at N-terminus.
Product Categories/Family for IFNG recombinant protein
Applications Tested/Suitable for IFNG recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for IFNG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16.9kDa (144aa), confirmed by MALDI-TOF. [Similar Products]
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
IFG; IFI
  [Similar Products]
NCBI Protein Information
interferon gamma
UniProt Protein Name
Interferon gamma
UniProt Synonym Protein Names
Immune interferon
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IFN-gamma  [Similar Products]
NCBI Summary for IFNG
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
UniProt Comments for IFNG
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Product References and Citations for IFNG recombinant protein
Sen GC, Lengyel P (1992) J. Biol. Chem. 267 (8):5017-5020; Tsutomu Arakawa, Yeuh-Rong Hsu (1987) Biochemistry. 26:5428-5432; Ernst Rinderknecht, et al (1984) J. Biol. Chem. 259 (11):6790-6797;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with IFNG recombinant protein
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