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IFNg western blot control :: Interferon Gamma (IFNg) Western Blot Control

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Catalog # MBS343051
Unit / Price
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  0.01 mg  /  $215 +1 FREE 8GB USB
IFNg western blot control
Product Name

Interferon Gamma (IFNg), Western Blot Control

Full Product Name

Interferon Gamma (IFNg) (Western Blot Control)

Product Synonym Names
Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
147570
3D Structure
ModBase 3D Structure for P01579
Purity/Purification
>= 95% (SDS PAGE)
Form/Format
Liquid
Buffer
Buffered 50% glycerol
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IFNg western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IFNg western blot control
IFN gamma is a potent multifunctional cytokine primarily produced by T cells and natural killer cells. IFN gamma exerts a variety of antiproliferative, immunoregulatory and pro-inflammatory biological activities in response to binding at specific cell surface receptors. Recombinant IFN gamma comprises a 143 amino acid fragment (24-166) corresponding to the mature soluble IFN gamma chain protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
NCBI/Uniprot data below describe general gene information for IFNg. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,348 Da
NCBI Official Full Name
interferon-gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
IFG; IFI
  [Similar Products]
NCBI Protein Information
interferon gamma
UniProt Protein Name
Interferon gamma
UniProt Synonym Protein Names
Immune interferon
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IFN-gamma  [Similar Products]
UniProt Entry Name
IFNG_HUMAN
NCBI Summary for IFNg
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
UniProt Comments for IFNg
IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family.

Protein type: Membrane protein, integral; Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity

Biological Process: adaptive immune response; apoptosis; cell cycle arrest; cell motility; cell surface receptor linked signal transduction; humoral immune response; negative regulation of epithelial cell differentiation; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of autophagy; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of cell proliferation; positive regulation of interleukin-12 production; positive regulation of interleukin-23 production; positive regulation of killing of cells of another organism; positive regulation of membrane protein ectodomain proteolysis; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of tyrosine phosphorylation of Stat1 protein; protein import into nucleus, translocation; regulation of insulin secretion; response to virus

Disease: Aplastic Anemia; Hepatitis C Virus, Susceptibility To; Human Immunodeficiency Virus Type 1, Susceptibility To; Mycobacterium Tuberculosis, Susceptibility To; Tuberous Sclerosis 2
Product References and Citations for IFNg western blot control
Schreiber, R.D. & Farrar, M.A. (1993) Gastroenterol. J. 28(4): 88- 94.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with IFNg western blot control
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