View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List IGFBP1 recombinant protein Catalog # MBS355801 Unit / Price 0.1 mg / $345 +1 FREE 8GB USB 1 mg / $1,070 +1 FREE 8GB USB 5x1 mg / $4,470 +5 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IGFBP1, Recombinant Protein Full Product Name IGFBP1 Product Gene Name IGFBP1 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM Y00856 mRNA Other Notes Small volumes of IGFBP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for IGFBP1. It may not necessarily be applicable to this product. NCBI GI # 4504615 NCBI GeneID 3484 NCBI GenBank Nucleotide # NM_000596.2 [Other Products] UniProt Secondary Accession # Q8IYP5; A4D2F4; D3DVL9[Other Products] UniProt Related Accession # P08833[Other Products] Molecular Weight 27,904 Da TOP NCBI Official Full Name insulin-like growth factor-binding protein 1 NCBI Official Synonym Full Names insulin like growth factor binding protein 1 NCBI Official Symbol IGFBP1 [Similar Products] NCBI Official Synonym Symbols AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1 [Similar Products] NCBI Protein Information insulin-like growth factor-binding protein 1 UniProt Protein Name Insulin-like growth factor-binding protein 1 UniProt Synonym Protein Names Placental protein 12; PP12 Protein Family Insulin-like growth factor-binding protein UniProt Gene Name IGFBP1 [Similar Products] UniProt Synonym Gene Names IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12 [Similar Products] UniProt Entry Name IBP1_HUMAN TOP NCBI Summary for IGFBP1 This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008] TOP UniProt Comments for IGFBP1 IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p12.3Cellular Component: extracellular regionMolecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding; receptor bindingBiological Process: cellular protein metabolic process; regulation of insulin-like growth factor receptor signaling pathway; signal transduction Research Articles on IGFBP1 1. Study shows that women with polycystic ovarian syndrome and endometrial cancer have an increased endometrial expression of genes (IGF1, IGFBP1 and PTEN) involved in the insulin signaling pathway compared with control women. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with IGFBP1 recombinant protein Reference Product PubMed Publications IGF1 recombinant protein >88 publications with IGFBP1 and IGF1 IGF2 recombinant protein >42 publications with IGFBP1 and IGF2 IGFBP4 recombinant protein >25 publications with IGFBP1 and IGFBP4 FOXO1 recombinant protein >21 publications with IGFBP1 and FOXO1 INS recombinant protein >6 publications with IGFBP1 and INS HIF1A recombinant protein >3 publications with IGFBP1 and HIF1A FOXA2 recombinant protein >2 publications with IGFBP1 and FOXA2 GCG recombinant protein >1 publications with IGFBP1 and GCG NR3C1 recombinant protein >1 publications with IGFBP1 and NR3C1 ATF4 recombinant protein >1 publications with IGFBP1 and ATF4 Pathways associated with IGFBP1 recombinant protein Products by Pathway Pathway Diagram ATF4 Activates Genes Pathway antibodies ATF4 Activates Genes Pathway Diagram Aryl Hydrocarbon Receptor Pathway antibodies Aryl Hydrocarbon Receptor Pathway Diagram FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram HIF-1-alpha Transcription Factor Network Pathway antibodies HIF-1-alpha Transcription Factor Network Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Myometrial Relaxation And Contraction Pathways antibodies Myometrial Relaxation And Contraction Pathways Diagram PERK Regulates Gene Expression Pathway antibodies PERK Regulates Gene Expression Pathway Diagram Photodynamic Therapy-induced HIF-1 Survival Signaling Pathway antibodies Photodynamic Therapy-induced HIF-1 Survival Signaling Pathway Diagram Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram Unfolded Protein Response (UPR) Pathway antibodies Unfolded Protein Response (UPR) Pathway Diagram Diseases associated with IGFBP1 recombinant protein Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >30 publications with IGFBP1 and Cardiovascular Diseases Liver Diseases Antibodies >27 publications with IGFBP1 and Liver Diseases Inflammation Antibodies >22 publications with IGFBP1 and Inflammation Endometriosis Antibodies >18 publications with IGFBP1 and Endometriosis Liver Neoplasms Antibodies >18 publications with IGFBP1 and Liver Neoplasms Carcinoma, Hepatocellular Antibodies >16 publications with IGFBP1 and Carcinoma, Hepatocellular Kidney Diseases Antibodies >16 publications with IGFBP1 and Kidney Diseases Necrosis Antibodies >15 publications with IGFBP1 and Necrosis Hyperglycemia Antibodies >15 publications with IGFBP1 and Hyperglycemia Fetal Growth Retardation Antibodies >14 publications with IGFBP1 and Fetal Growth Retardation Organs/Tissues associated with IGFBP1 recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >266 publications with IGFBP1 and Blood Uterus Antibodies >123 publications with IGFBP1 and Uterus Liver Antibodies >101 publications with IGFBP1 and Liver Placenta Antibodies >98 publications with IGFBP1 and Placenta Embryonic Tissue Antibodies >42 publications with IGFBP1 and Embryonic Tissue Bone Antibodies >34 publications with IGFBP1 and Bone Lung Antibodies >15 publications with IGFBP1 and Lung Brain Antibodies >13 publications with IGFBP1 and Brain Pancreas Antibodies >11 publications with IGFBP1 and Pancreas Skin Antibodies >6 publications with IGFBP1 and Skin TOP © 2006-24 MyBioSource.com. 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