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IgG secondary antibody :: IgG Fc fragment Secondary Antibody

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Catalog # MBS719658
Unit / Price
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  0.5 mg  /  $160 +1 FREE 8GB USB
Western Blot
Product Name

IgG Fc fragment, Secondary Antibody

Popular Item
Full Product Name

Rabbit anti-Human IgG Fc fragment polyclonal Antibody, HRP conjugated

Product Synonym Names
Fragment crystallizable region
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS719658 COA
MBS719658 Technical Datasheet
Species Reactivity
Caprylic Acid Ammonium Sulfate Precipitation purified, HRP conjugated

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IgG secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IgG secondary antibody
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2-4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues.
Applications Tested/Suitable for IgG secondary antibody
ELISA (EIA), Western Blot (WB)

Western Blot of IgG secondary antibody
Western Blot
Positive WB detected in Recombinant
protein (80ng, 40ng, 20ng, 10ng)
All lanes: Human IgG Fc antibody;
HRPconjugated at 1:1000
Predicted band size: 35 kDa
Observed band size: 35 kDa
IgG secondary antibody Western Blot (WB) image
NCBI Summary for IgG
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
UniProt Comments for IgG
FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells.

Protein type: Cell surface; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: plasma membrane; integral to membrane

Molecular Function: IgG binding

Biological Process: innate immune response

Disease: Systemic Lupus Erythematosus; Malaria, Susceptibility To
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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