NP_034674.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,485 Da
NCBI Official Full Name
indian hedgehog protein isoform 1 preproprotein
NCBI Official Synonym Full Names
Indian hedgehog
NCBI Official Synonym Symbols
NCBI Protein Information
indian hedgehog protein
UniProt Protein Name
Indian hedgehog protein
UniProt Synonym Protein Names
HHG-2
UniProt Synonym Gene Names
UniProt Entry Name
IHH_MOUSE
UniProt Comments for Ihh
IHH: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP). Expressed in embryonic lung, and in adult kidney and liver. Belongs to the hedgehog family.
Cellular Component: extracellular region; membrane; plasma membrane; proteinaceous extracellular matrix
Molecular Function: calcium ion binding; hydrolase activity; metal ion binding; patched binding; peptidase activity; protein binding
Biological Process: bone resorption; camera-type eye development; cartilage development; cell communication; cell differentiation; cell fate specification; cell maturation; cell-cell signaling; embryonic camera-type eye morphogenesis; embryonic development; embryonic digestive tract morphogenesis; embryonic digit morphogenesis; embryonic pattern specification; heart looping; in utero embryonic development; intein-mediated protein splicing; morphogenesis of a branching structure; multicellular organism growth; multicellular organismal development; negative regulation of alpha-beta T cell differentiation; negative regulation of apoptosis; negative regulation of cell differentiation; negative regulation of eye pigmentation; negative regulation of immature T cell proliferation in the thymus; negative regulation of signal transduction; negative regulation of T cell differentiation in the thymus; neuron development; ossification; osteoblast differentiation; pancreas development; pattern specification process; patterning of blood vessels; positive regulation of alpha-beta T cell differentiation; positive regulation of cell proliferation; positive regulation of chondrocyte differentiation; positive regulation of collagen biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; positive regulation of T cell differentiation in the thymus; positive regulation of transcription from RNA polymerase II promoter; proteoglycan metabolic process; proteolysis; regulation of cell differentiation; regulation of growth; skeletal development; smooth muscle development; smoothened signaling pathway; vasculature development; vitelline membrane formation
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Products associated with Ihh elisa kit
Pathways associated with Ihh elisa kit
Diseases associated with Ihh elisa kit
Organs/Tissues associated with Ihh elisa kit
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