AAV41220.1
[Other Products]
NCBI Official Full Name
interleukin-17, partial
UniProt Protein Name
Interleukin-17
UniProt Synonym Protein Names
Interleukin-17
UniProt Entry Name
Q5QEX9_HUMAN
NCBI Summary for IL-17
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
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