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IL-2 western blot control :: Interleukin-2 (IL-2) Western Blot Control

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Catalog # MBS343068
Unit / Price
  0.01 mg  /  $225 +1 FREE 8GB USB
IL-2 western blot control
Product Name

Interleukin-2 (IL-2), Western Blot Control

Also Known As

Interleukin-2 (IL-2) (Western Blot Control)

Product Synonym Names
IL-2; T-Cell Growth Factor; TCGF.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
153
OMIM
147680
3D Structure
ModBase 3D Structure for P60568
Purity/Purification
>= 95% (SDS PAGE)
Form/Format
Liquid
Buffer
Buffered 50% glycerol
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IL-2 western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IL-2 western blot control
Interleukin-2 is a pleiotropic cytokine produced primarily by mitogenic or antigen activated T lymphocytes. IL-2 plays a key role in T cell proliferation and promotes the proliferation, expansion and differentiation of a wide variety of antigen specific cells. Recombinant Interleukin-2 comprises a 133 amino acid fragment (21-153) corresponding to the mature Interleukin-2 protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
NCBI/Uniprot data below describe general gene information for IL-2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,628 Da
NCBI Official Full Name
interleukin-2
NCBI Official Synonym Full Names
interleukin 2
NCBI Official Symbol
NCBI Official Synonym Symbols
IL-2; TCGF; lymphokine
  [Similar Products]
NCBI Protein Information
interleukin-2
UniProt Protein Name
Interleukin-2
UniProt Synonym Protein Names
T-cell growth factor; TCGF; INN: Aldesleukin
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL-2; TCGF  [Similar Products]
UniProt Entry Name
IL2_HUMAN
NCBI Summary for IL-2
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
UniProt Comments for IL-2
IL2: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Belongs to the IL-2 family.

Protein type: Oncoprotein; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q26-q27

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; growth factor activity; interleukin-2 receptor binding; kinase activator activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: cell adhesion; cell-cell signaling; immune response; MAPKKK cascade; natural killer cell activation; negative regulation of apoptosis; negative regulation of B cell apoptosis; positive regulation of activated T cell proliferation; positive regulation of B cell proliferation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of inflammatory response; positive regulation of interleukin-17 production; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of Stat5 protein; T cell differentiation
Product References and Citations for IL-2 western blot control
Fletcher, M. & Goldstein, A.L. (1987) Lymphokine Res. 6(1): 45- 57. Jelinek, D.F. et al., (1986) Eur. J. Immunol. 16(8): 925- 932.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Organs/Tissues associated with IL-2 western blot control
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