Interleukin (IL), are a group of naturally occurring proteins that mediate communication between cells. Interleukins are cytokines, small proteins produced and secreted mainly by CD3+ and CD4+ T lymphocytes. Interleukins promote development and differentiation of natural killer cells, T and B lymphocytes and haematopoietic stem cells. They are not stored within cells but are instead secreted rapidly, and briefly, in response to a stimulus, such as an infectious agent. Fifteen different types of interleukins are known, designated numerically, IL-1 through IL-15.
Promotes development and differentiation of natural killer cells, T and B lymphocytes and haematopoietic stem cells. Involved in systemic inflammation and immune system modulation. Plays an important roles in fighting cancer, infectious disease and other diseases. Involved in cell signaling, particularly in the immune and hemopoietic systems. Directing other immune cells to divide and differentiate. Each interleukin acts on a specific group of cells that express its cognate receptors. Once an interleukin has been produced, it travels to its target cell and binds to it via a receptor molecule on the cell�s surface. This interaction triggers a cascade of signals within the target cell that ultimately alter the cell�s behaviour. Regulate cell growth, differentiation, and motility. Involved in systemic inflammation and immune system modulation. Produced by many cells and interact with a host of cells not involved in immunity. Involved in many other physiological functions. The set of interleukins stimulated by a specific infectious agent determines which cells will respond to the infection and influences some of the clinical manifestations of the disease.
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