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IL13 recombinant protein :: Interleukin 13 Recombinant Protein

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Catalog # MBS2034519 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $150 +1 FREE 8GB USB
  0.05 mg  /  $285 +1 FREE 8GB USB
  0.1 mg  /  $445 +1 FREE 8GB USB
  0.2 mg  /  $550 +1 FREE 8GB USB
  0.5 mg  /  $1,060 +1 FREE 8GB USB
  1 mg  /  $1,580 +1 FREE 8GB USB
Product Name

Interleukin 13 (IL13), Recombinant Protein

Popular Item
Also Known As

Recombinant Interleukin 13 (IL13)

Product Synonym Gene Name
ALRH; BHR1; P600; IL-13; NC30[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
146
OMIM
147683
Host
E Coli
Source: Prokaryotic expression
Species Reactivity
Mouse
Purity/Purification
> 90%
Form/Format
Freeze-dried powder
Usage
Reconstitute in PBS or others.
Endotoxin Level
< 1.0EU per 1ug (determined by the LAL method)
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Residues & Tags
N-terminal His Tag
Subcellular Location
Secreted
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of IL13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for IL13 recombinant protein
SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP)

Sequence Information of IL13 recombinant protein
IL13 recombinant protein Sequence Information image
NCBI/Uniprot data below describe general gene information for IL13. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,816 Da
NCBI Official Full Name
interleukin-13
NCBI Official Synonym Full Names
interleukin 13
NCBI Official Symbol
NCBI Official Synonym Symbols
P600; IL-13
  [Similar Products]
NCBI Protein Information
interleukin-13
UniProt Protein Name
Interleukin-13
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NC30; IL-13  [Similar Products]
UniProt Entry Name
IL13_HUMAN
NCBI Summary for IL13
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
UniProt Comments for IL13
IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: extracellular region; extracellular space

Molecular Function: interleukin-13 receptor binding; protein binding

Biological Process: cell motility; cell-cell signaling; positive regulation of B cell proliferation; positive regulation of immunoglobulin production; positive regulation of macrophage activation; positive regulation of mast cell degranulation

Disease: Allergic Rhinitis; Asthma, Susceptibility To
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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