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IL1B recombinant protein :: Interleukin 1 beta Recombinant Protein

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Catalog # MBS650404
Unit / Price
  0.01 mg  /  $430 +1 FREE 8GB USB
IL1B recombinant protein
Product Name

Interleukin 1 beta (IL1B), Recombinant Protein

Full Product Name

Interleukin 1 beta, Recombinant, Human (IL-1b) (Human 293 Cells)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 2; NC_013670.1 (97614341..97618580, complement)
3D Structure
ModBase 3D Structure for P14628
Purity/Purification
Highly Purified
95% as determined by SDS-PAGE and HPLC.
Form/Format
Supplied as a lyophilized powder from MES pH 6.0, 50mM NaCl. Reconstitute with sterile dH2O, 0.1% endotoxin-free recombinant HSA.
Activity
The specific activity was determined by the dose-dependent stimulation of the proliferation
of mouse D10S cells.
Specific Activity
~30pg/ml ED50
Endotoxin Level
1EU/ug (LAL)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O, 0.1% endotoxin-free recombinant HSA. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at 4 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of IL1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IL1B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
interleukin-1 beta
NCBI Official Symbol
NCBI Official Synonym Symbols
IL1-BETA
  [Similar Products]
NCBI Protein Information
interleukin-1 beta; IL-1 beta; interleukin 1 beta; lymphocyte proliferation-potentiating factor
UniProt Protein Name
Interleukin-1 beta
UniProt Synonym Protein Names
Lymphocyte proliferation-potentiating factor
Protein Family
UniProt Gene Name
UniProt Entry Name
IL1B_RABIT
UniProt Comments for IL1B
Function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Subunit structure: Monomer.

Subcellular location: Secreted. Note: The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

Domain: The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.

Sequence similarities: Belongs to the IL-1 family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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