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IL1RN recombinant protein

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Catalog # MBS204721
Unit / Price
  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

IL1RN, Recombinant Protein

Also Known As

IL1RN, 27-178aa, Mouse, His tag, E Coli

Product Synonym Names
Interleukin 1 receptor antagonist; F630041P17Rik; IL-1ra
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
178
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMRPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEK IDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEED KRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ
3D Structure
ModBase 3D Structure for P25085
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Mouse
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of IL1RN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IL1RN recombinant protein
Interleukin 1 receptor antagonist (IL1RN), also known as IL1-RA, is a member of the interleukin 1 cytokine family. IL1RN may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. IL1RN is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Recombinant mouse IL1RN protein, fused to His-tag at N-terminus was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for IL1RN recombinant protein
Applications Tested/Suitable for IL1RN recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for IL1RN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20.0 kDa (177aa), confirmed by MALDI-TOF
NCBI Official Full Name
interleukin-1 receptor antagonist protein isoform 2
NCBI Official Synonym Full Names
interleukin 1 receptor antagonist
NCBI Official Symbol
Il1rn  [Similar Products]
NCBI Official Synonym Symbols
IL-1ra; F630041P17Rik
  [Similar Products]
NCBI Protein Information
interleukin-1 receptor antagonist protein
UniProt Protein Name
Interleukin-1 receptor antagonist protein
UniProt Synonym Protein Names
IL1 inhibitor
UniProt Gene Name
Il1rn  [Similar Products]
UniProt Synonym Gene Names
Il-1ra; IL-1RN; IL-1ra; IRAP  [Similar Products]
UniProt Comments for IL1RN
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Product References and Citations for IL1RN recombinant protein
Steinkasserer A., et al. (1992) Genomics. 13 (3):654-7.; Langdahl BL., et al. (2000) J Bone Miner Res. 15 (3): 403-14.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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