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IL2 cdna clone

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Catalog # MBS1267020
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
IL2 cdna clone
Product Name

IL2, cDNA Clone

Popular Item
Full Product Name

IL2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtacagga tgcaactcct gtcttgcatt gcactaagtc ttgcacttgt cacaaacagt gcacctactt caagttctac aaagaaaaca cagctacaac tggagcattt actgctggat ttacagatga ttttgaatgg aattaataat tacaagaatc ccaaactcac caggatgctc acatttaagt tttacatgcc caagaaggcc acagaactga aacatcttca gtgtctagaa gaagaactca aacctctgga ggaagtgcta aatttagctc aaagcaaaaa ctttcactta agacccaggg acttaatcag caatatcaac gtaatagttc tggaactaaa gggatctgaa acaacattca tgtgtgaata tgctgatgag acagcaacca ttgtagaatt tctgaacaga tggattacct tttgtcaaag catcatctca acactgactt ga
OMIM
147680
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of IL2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IL2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,628 Da
NCBI Official Full Name
Homo sapiens interleukin 2, mRNA
NCBI Official Synonym Full Names
interleukin 2
NCBI Official Symbol
NCBI Official Synonym Symbols
IL-2; TCGF; lymphokine
  [Similar Products]
NCBI Protein Information
interleukin-2
UniProt Protein Name
Interleukin-2
UniProt Synonym Protein Names
T-cell growth factor; TCGF; INN: Aldesleukin
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL-2; TCGF  [Similar Products]
UniProt Entry Name
IL2_HUMAN
NCBI Summary for IL2
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
UniProt Comments for IL2
IL2: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Belongs to the IL-2 family.

Protein type: Secreted; Cytokine; Secreted, signal peptide; Oncoprotein

Chromosomal Location of Human Ortholog: 4q26-q27

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; growth factor activity; interleukin-2 receptor binding; kinase activator activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: cell adhesion; cell-cell signaling; immune response; MAPKKK cascade; natural killer cell activation; negative regulation of apoptosis; negative regulation of B cell apoptosis; positive regulation of activated T cell proliferation; positive regulation of B cell proliferation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of inflammatory response; positive regulation of interleukin-17 production; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of Stat5 protein; T cell differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with IL2 cdna clone
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