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IL21R elisa kit :: Human interleukin 21 receptor ELISA Kit

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Catalog # MBS917921
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IL21R elisa kit
Product Name

interleukin 21 receptor (IL21R), ELISA Kit

Also Known As

Human Interleukin-21 receptor, IL21R ELISA Kit

Product Synonym Names
Human Interleukin-21 receptor (IL21R) ELISA kit; MGC10967; NILR; ; interleukin 21 receptor
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Sequence Length
538
OMIM
gene 615207
3D Structure
ModBase 3D Structure for Q9HBE5
Species Reactivity
Specificity
This assay has high sensitivity and excellent specificity for detection of Human IL21R. No significant cross-reactivity or interference between Human IL21R and analogues was observed.
Samples
Serum, plasma, tissue homogenates
Assay Type
Sandwich
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of IL21R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forIL21Rpurchase
MBS917921 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 21 receptor (IL21R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL21R. The ELISA analytical biochemical technique of the MBS917921 kit is based on IL21R antibody-IL21R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL21R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL21R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
IL21R elisa kit
For Sample For the quantitative determination of human interleukin-21 receptor (IL21R) concentrations in serum, plasma, tissue homogenates.

PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL21R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL21R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL21R is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL21R bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS917921. Click to request current manual
NCBI/Uniprot data below describe general gene information for IL21R. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,130 Da
NCBI Official Full Name
interleukin-21 receptor isoform 1
NCBI Official Synonym Full Names
interleukin 21 receptor
NCBI Official Symbol
IL21R  [Similar Products]
NCBI Official Synonym Symbols
NILR; CD360
  [Similar Products]
NCBI Protein Information
interleukin-21 receptor; IL-21 receptor; novel interleukin receptor
UniProt Protein Name
Interleukin-21 receptor
UniProt Synonym Protein Names
Novel interleukin receptor; CD_antigen: CD360
Protein Family
UniProt Gene Name
IL21R  [Similar Products]
UniProt Synonym Gene Names
NILR; UNQ3121/PRO10273; IL-21 receptor; IL-21R  [Similar Products]
UniProt Entry Name
IL21R_HUMAN
NCBI Summary for IL21R
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
UniProt Comments for IL21R
IL21R: This is a receptor for interleukin-21

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11

Cellular Component: integral to membrane

Molecular Function: interleukin-21 receptor activity

Biological Process: natural killer cell activation

Disease: Ige Responsiveness, Atopic; Il21r Immunodeficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withIL21R elisa kit
 Reference Product  PubMed Publications
 JAK1 elisa kit  >11 publications with IL21R and JAK1
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